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Cola Dissolution Therapy via Ileus Tube Was Effective for Ileus Secondary to Small Bowel Obstruction Induced by an Enterolith.


ABSTRACT: An 87-year-old bedridden woman developed intestinal obstruction caused by an enterolith or bezoar. Since the patient refused surgery, we administered 1,000 mL/day of cola via an ileus tube to dissolve the stone. Occlusion of the small intestine disappeared on day 6. The excreted stones contained calcium phosphate, which is typical of enteroliths. We later confirmed that the retrieved stones could be dissolved in cola (Coca-Cola®, pH 1.9) as well as 0.10 and 0.010 mol/L hydrochloric acid (pH 1.0 and 2.0, respectively) and food-grade vinegar (pH 2.6). These findings suggest that the enteroliths were dissolved by an acid-base reaction.

SUBMITTER: Komaki Y 

PROVIDER: S-EPMC6761349 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Cola Dissolution Therapy via Ileus Tube Was Effective for Ileus Secondary to Small Bowel Obstruction Induced by an Enterolith.

Komaki Yuga Y   Kanmura Shuji S   Tanaka Akihito A   Nakashima Mari M   Komaki Fukiko F   Iwaya Hiromichi H   Arima Shiho S   Sasaki Fumisato F   Nasu Yuichiro Y   Tanoue Shiroh S   Hashimoto Shinichi S   Ido Akio A  

Internal medicine (Tokyo, Japan) 20190522 17


An 87-year-old bedridden woman developed intestinal obstruction caused by an enterolith or bezoar. Since the patient refused surgery, we administered 1,000 mL/day of cola via an ileus tube to dissolve the stone. Occlusion of the small intestine disappeared on day 6. The excreted stones contained calcium phosphate, which is typical of enteroliths. We later confirmed that the retrieved stones could be dissolved in cola (Coca-Cola<sup>®</sup>, pH 1.9) as well as 0.10 and 0.010 mol/L hydrochloric ac  ...[more]

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