Ontology highlight
ABSTRACT:
SUBMITTER: Asare-Werehene M
PROVIDER: S-EPMC6763481 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Asare-Werehene Meshach M Communal Laudine L Carmona Euridice E Le Tien T Provencher Diane D Mes-Masson Anne-Marie AM Tsang Benjamin K BK
Scientific reports 20190926 1
Ovarian cancer (OVCA) patients with suboptimal residual disease (RD) and advanced stages have poor survival. pGSN is an actin binding protein which protects OVCA cells from cisplatin-induced death. There is an urgent need to discover reliable biomarkers to optimize individualized treatment recommendations. 99 plasma samples with pre-determined CA125 were collected from OVCA patients and pGSN assayed using sandwich-based ELISA. Associations between CA125, pGSN and clinicopathological parameters w ...[more]