Ontology highlight
ABSTRACT:
SUBMITTER: Journot CMA
PROVIDER: S-EPMC6764109 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
ACS nano 20190820 9
We describe the triggered assembly of a bioinspired DNA origami meshwork on a lipid membrane. DNA triskelia, three-armed DNA origami nanostructures inspired by the membrane-modifying protein clathrin, are bound to lipid mono- and bilayers using cholesterol anchors. Polymerization of triskelia, triggered by the addition of DNA staples, links triskelion arms to form a mesh. Using transmission electron microscopy, we observe nanoscale local deformation of a lipid monolayer induced by triskelion pol ...[more]