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ABSTRACT:
SUBMITTER: Giubertoni G
PROVIDER: S-EPMC6767362 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Giubertoni Giulia G Koenderink Gijsje H GH Bakker Huib J HJ
The journal of physical chemistry. A 20190912 38
We use two-dimensional infrared spectroscopy to study the interactions between the amide and carboxylate anion groups of hyaluronan polymers at neutral pH. The spectra reveal the presence of intrachain hydrogen bonds between the amide and carboxylate anion groups in aqueous solution. We determine the relative orientation of the amide and carboxylate anion groups when forming this hydrogen bond and quantify the fraction of amide groups that participate in hydrogen bonding. We find that a variatio ...[more]