Ontology highlight
ABSTRACT:
SUBMITTER: Jepma M
PROVIDER: S-EPMC6768437 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Jepma Marieke M Koban Leonie L van Doorn Johnny J Jones Matt M Wager Tor D TD
Nature human behaviour 20181029 11
Beliefs and expectations often persist despite evidence to the contrary. Here we examine two potential mechanisms underlying such 'self-reinforcing' expectancy effects in the pain domain: modulation of perception and biased learning. In two experiments, cues previously associated with symbolic representations of high or low temperatures preceded painful heat. We examined trial-to-trial dynamics in participants' expected pain, reported pain and brain activity. Subjective and neural pain responses ...[more]