Ontology highlight
ABSTRACT:
SUBMITTER: Susman L
PROVIDER: S-EPMC6768856 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Susman Lee L Brenner Naama N Barak Omri O
Nature communications 20190930 1
What is the physiological basis of long-term memory? The prevailing view in Neuroscience attributes changes in synaptic efficacy to memory acquisition, implying that stable memories correspond to stable connectivity patterns. However, an increasing body of experimental evidence points to significant, activity-independent fluctuations in synaptic strengths. How memories can survive these fluctuations and the accompanying stabilizing homeostatic mechanisms is a fundamental open question. Here we e ...[more]