T-cell-derived cytokines enhance the antigen-presenting capacity of human neutrophils.
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ABSTRACT:
SUBMITTER: Samadi N
PROVIDER: S-EPMC6771661 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
T-cell-derived cytokines enhance the antigen-presenting capacity of human neutrophils.
Samadi Nazanin N Polak Dominika D Kitzmüller Claudia C Steinberger Peter P Zlabinger Gerhard J GJ Jahn-Schmid Beatrice B Bohle Barbara B
European journal of immunology 20190806 9
Activated allergen-specific Th2 and Th1 cells release cytokines that transform neutrophils into functional APCs characterized by the expression of HLA-DR and CD58 as well as enhanced survival and antigen uptake, irrespectively of the presence of IL-10, which reduces allergen uptake by neutrophils. ...[more]
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