Ontology highlight
ABSTRACT:
SUBMITTER: Addo RK
PROVIDER: S-EPMC6771914 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Addo Richard K RK Heinrich Frederik F Heinz Gitta Anne GA Schulz Daniel D Sercan-Alp Özen Ö Lehmann Katrin K Tran Cam Loan CL Bardua Markus M Matz Mareen M Löhning Max M Hauser Anja E AE Kruglov Andrey A Chang Hyun-Dong HD Durek Pawel P Radbruch Andreas A Mashreghi Mir-Farzin MF
European journal of immunology 20190607 9
Bone marrow (BM) stromal cells are important in the development and maintenance of cells of the immune system. Using single cell RNA sequencing, we here explore the functional and phenotypic heterogeneity of individual transcriptomes of 1167 murine BM mesenchymal stromal cells. These cells exhibit a tremendous heterogeneity of gene expression, which precludes the identification of defined subpopulations. However, according to the expression of 108 genes involved in the communication of stromal c ...[more]