Dataset Information

A brief version of the questionnaire of olfactory disorders in patients with chronic rhinosinusitis.

ABSTRACT:

Background

The Questionnaire of Olfactory Disorders-Negative Statements (QOD-NS) is a valuable instrument in the measurement of olfactory-specific quality of life (QOL). In the clinical setting, patients can be overwhelmed with the time required to complete questionnaires. Our objective was to develop a brief version of the QOD-NS to streamline clinical care and research.

Methods

QOD-NS scores from 221 subjects were used to determine which subset of the 17 QOD-NS questions best correlated with total and subdomain QOD-NS scores. An initial pool of 11 questions was made by removing items with ρ < 0.80 to their respective subdomain scores. Next, 500 bootstrapped samples were taken. On each sampe, an all-subsets regression was performed with total QOD-NS scores and QOD-NS subdomain scores as the outcomes. From this, our "top" and "bottom" 10 subsets were identified based on mean r² value, representation in bootstrap analysis, and number of items.

Results

All of our top subsets had excellent correlation with total and subdomain QOD-NS scores (mean r² > 0.90). Our top choice has 7 total questions, is representative of all subdomains, has a mean r² = 0.92, and was represented in 323 of our 500 bootstrapped samples. The worst-performing subset has 5 items, mean r² = 0.81, and was represented in only 1 bootstrapped sample.

Conclusions

Using less than half of the questions in the QOD-NS, excellent correlations with both total and domain-specific scores are achieved. A brief version of the QOD-NS may prove useful in future clinical and research settings.

SUBMITTER: Mattos JL

PROVIDER: S-EPMC6773507 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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Publications

A brief version of the questionnaire of olfactory disorders in patients with chronic rhinosinusitis.

Mattos Jose L JL Edwards Campbell C Schlosser Rodney J RJ Hyer Madison M Mace Jess C JC Smith Timothy L TL Soler Zachary M ZM

International forum of allergy & rhinology 20190820 10

<h4>Background</h4>The Questionnaire of Olfactory Disorders-Negative Statements (QOD-NS) is a valuable instrument in the measurement of olfactory-specific quality of life (QOL). In the clinical setting, patients can be overwhelmed with the time required to complete questionnaires. Our objective was to develop a brief version of the QOD-NS to streamline clinical care and research.<h4>Methods</h4>QOD-NS scores from 221 subjects were used to determine which subset of the 17 QOD-NS questions best co ...[more]

PMID: 31430061

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Project description:Abstract Background The comprehensive counseling of patients with olfactory dysfunctions requires accurate diagnosis. The recommendations include subjective assessment. The Questionnaire of Olfactory Disorders (QOD) is a disease‐specific questionnaire for the subjective evaluation of olfactory dysfunctions. Material The study included 54 patients with olfactory dysfunctions, who were recruited to the study group (SG). The other 47 patients without the history of olfactory dysfunction and nasal cavity pathology were voluntarily allocated to the control group (CG). The protocol of the study was introduced to each patient and included: olfactory testing with Sniffin' Stick test, fulfillment of the Polish version of World Health Organization Quality of Life brief questionnaire and completing of the Polish version of the QOD. All participants (101) were invited for refilling the QOD questionnaire after 2 weeks for the test–retest statistics. Results The Polish QOD statements were significantly correlated and met the requirement by having test–retest correlation larger than 0.7. We found that internal consistency of the test measured by Cronbach's alpha coefficient was very high. The mean scores of the QOD test in normosmic SG patients were compared with corresponding scores in normosmic CG patients using U Mann–Whitney test. The analysis revealed statistically significant differences on mean QOD scores for each domains except QOD‐S between both groups. Conclusions The Polish version of the QOD demonstrated high rate of the validity and the reliability. This instrument may be widely used in research projects and clinical practice concerning olfactory disorders in Polish patients. Level of Evidence NA. The QOD is a disease‐specific questionnaire for subjective evaluation of olfactory dysfunctions. Presented Polish version of the QOD demonstrated high rates of the validity and the reliability. From now, this instrument may be widely used in research projects and clinical practice concerning olfactory disorders in Polish patients.

Project description:Background Olfaction plays an enormous role in every aspect of life including health, emotions, social life, and safety. This is why olfactory dysfunction will leave a great impact on a person’s life. During the recent pandemic hit of coronavirus 2019 (COVID-19), much importance was given to olfaction and its sequelae post-COVID-19. There is various questionnaire being used for determining olfactory disorders worldwide. In Malaysia, Malay language is widely conversed among the local population hence an assessment tool for an olfactory specific quality of life is necessary. Method This is a cross-sectional study performed in the Otorhinolaryngology clinic in a tertiary hospital. The short Questionnaire of Olfactory Disorders-Negative Statements (sQOD-NS) is a validated questionnaire that is a simple and easy tool to assess the impact of olfactory dysfunction in daily life. The original version of the short Questionnaire of Olfactory Disorders-Negative Statements (sQOD-NS) questionnaire was translated into the Malay language. A forward-backwards translation, validity, and reliability study was done on this questionnaire. A Malay version of sQOD-NS was responded to by a total of 70 participants including 35 patients of normosia and 35 patients with smell dysfunction and repeated after 2 weeks via phone call response. The discriminant validity, internal consistency, and test re-test reliability were assessed. Results The pilot study revealed that participants who were normosmic had a higher mean score than smell dysfunction. A Student t test shows mean 20.5 ± 1.22 in normosmic group and 6.06 ± 2.41 in hyposmic group which are significant with p value of < 0.01. The coefficient of correlation (r) between test and retest scores was 0.77 (P < 0.001). Conclusion The Malay translation of sQOD-NS is a validated questionnaire that can be used both in clinical practice and in academics. Supplementary Information The online version contains supplementary material available at 10.1186/s43163-022-00265-3.

Dataset Information

A brief version of the questionnaire of olfactory disorders in patients with chronic rhinosinusitis.

Background

Methods

Results

Conclusions

Publications

A brief version of the questionnaire of olfactory disorders in patients with chronic rhinosinusitis.

Similar Datasets

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