Ontology highlight
ABSTRACT:
SUBMITTER: Li L
PROVIDER: S-EPMC6773729 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Li Lingling L Zhang Xinan X Tian Tianhai T Pang Liuyong L
Scientific reports 20191001 1
Genomic instability plays a significant role in lung cancer. Although substantial research has been conducted using both clinical and theoretical studies, it is still a hotly debated issue to whether genomic instability is necessary or whether genomic instability precedes oncogenes activation and tumor suppressor genes inactivation for lung cancer. In response to this issue, we come up with a mathematical model incorporating effects of genomic instability to investigate the genomic instability p ...[more]