The use of platelet-rich plasma in oral surgery: a systematic review and meta-analysis.

ABSTRACT: BACKGROUND:The aim of this systematic review and meta-analysis was to evaluate the benefit of platelet rich plasma (PRP) in oral surgery. MATERIALS AND METHODS:We performed a systematic search of the literature. The GRADE system was used to assess the certainty of the body of evidence. RESULTS:We found 21 randomised controlled trials that met our inclusion criteria: 12 studies included patients with periodontal defects, five studies focused on healing of extraction sockets, three studies on sinus lift augmentation, and one study on periapical osseous defects. However, for the quantitative synthesis (meta-analysis), we evaluated "periodontal defects" studies only, since for other clinical contexts the number of studies were too low and the procedural heterogeneity was too high to allow pool

SUBMITTER: Franchini M 

PROVIDER: S-EPMC6774927 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature