Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.
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ABSTRACT:
SUBMITTER: Odorico J
PROVIDER: S-EPMC6775764 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Publications
Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.
Odorico Jon J Markmann James J Melton Douglas D Greenstein Julia J Hwa Albert A Nostro Cristina C Rezania Alireza A Oberholzer Jose J Pipeleers Daniel D Yang Luhan L Cowan Chad C Huangfu Danwei D Egli Dieter D Ben-David Uri U Vallier Ludovic L Grey Shane T ST Tang Qizhi Q Roep Bart B Ricordi Camilo C Naji Ali A Orlando Giuseppe G Anderson Daniel G DG Poznansky Mark M Ludwig Barbara B Tomei Alice A Greiner Dale L DL Graham Melanie M Carpenter Melissa M Migliaccio Giovanni G D'Amour Kevin K Hering Bernhard B Piemonti Lorenzo L Berney Thierry T Rickels Mike M Kay Thomas T Adams Ann A
Transplantation 20180801 8
Beta cell replacement has the potential to restore euglycemia in patients with insulin-dependent diabetes. Although great progress has been made in establishing allogeneic islet transplantation from deceased donors as the standard of care for those with the most labile diabetes, it is also clear that the deceased donor organ supply cannot possibly treat all those who could benefit from restoration of a normal beta cell mass, especially if immunosuppression were not required. Against this backgro ...[more]
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