Synergistic Association of House Endotoxin Exposure and Ambient Air Pollution with Asthma Outcomes.

ABSTRACT: Rationale: House endotoxin and ambient air pollution are risk factors for asthma; however, the effects of their coexposure on asthma are not well characterized.Objectives: To examine potential synergistic associations of coexposure to house dust endotoxin and ambient air pollutants with asthma outcomes.Methods: We analyzed data of 6,488 participants in the National Health and Nutrition Examination Survey 2005-2006. Dust from bedding and bedroom floor was analyzed for endotoxin content. The Community Multiscale Air Quality Modeling System (CMAQ) and Downscaler Model data were used to determine annual average particulate matter ≤2.5 μm in aerodynamic diameter (PM_2.5), ozone (O₃), and nitrogen dioxide (NO₂) exposures at participants' resid

SUBMITTER: Mendy A 

PROVIDER: S-EPMC6775869 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature