Ontology highlight
ABSTRACT:
SUBMITTER: Loth K
PROVIDER: S-EPMC6776556 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Loth Karine K Largillière Justine J Coste Franck F Culard Françoise F Landon Céline C Castaing Bertrand B Delmas Agnès F AF Paquet Françoise F
Scientific reports 20191003 1
MC1, a monomeric nucleoid-associated protein (NAP), is structurally unrelated to other DNA-binding proteins. The protein participates in the genome organization of several Euryarchaea species through an atypical compaction mechanism. It is also involved in DNA transcription and cellular division through unknown mechanisms. We determined the 3D solution structure of a new DNA-protein complex formed by MC1 and a strongly distorted 15 base pairs DNA. While the protein just needs to adapt its confor ...[more]