Ontology highlight
ABSTRACT:
SUBMITTER: de Vries RJ
PROVIDER: S-EPMC6776681 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Nature biotechnology 20190909 10
The inability to preserve vascular organs beyond several hours contributes to the scarcity of organs for transplantation<sup>1,2</sup>. Standard hypothermic preservation at +4 °C (refs. <sup>1,3</sup>) limits liver preservation to less than 12 h. Our group previously showed that supercooled ice-free storage at -6 °C can extend viable preservation of rat livers<sup>4,5</sup> However, scaling supercooling preservation to human organs is intrinsically limited because of volume-dependent stochastic ...[more]