Ontology highlight
ABSTRACT:
SUBMITTER: Moreno-Mendoza D
PROVIDER: S-EPMC6777534 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Moreno-Mendoza Daniel D Casamonti Elena E Paoli Donatella D Chianese Chiara C Riera-Escamilla Antoni A Giachini Claudia C Fino Maria Grazia MG Cioppi Francesca F Lotti Francesco F Vinci Serena S Magini Angela A Ars Elisabet E Sanchez-Curbelo Josvany J Ruiz-Castane Eduard E Lenzi Andrea A Lombardo Francesco F Krausz Csilla C
European journal of human genetics : EJHG 20190503 10
The association between impaired spermatogenesis and TGCT has stimulated research on shared genetic factors. Y chromosome-linked partial AZFc deletions predispose to oligozoospermia and were also studied in TGCT patients with controversial results. In the largest study reporting the association between gr/gr deletion and TGCT, sperm parameters were unknown. Hence, it remains to be established whether this genetic defect truly represents a common genetic link between TGCT and impaired sperm produ ...[more]