Ontology highlight
ABSTRACT:
SUBMITTER: Luo QS
PROVIDER: S-EPMC6779634 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20171101 11
<h4>Objective</h4>To investigate the role of α-enolase (ENO1) in regulating glucose metabolism and cell growth in human glioma cells.<h4>Methods</h4>Glucose uptake and lactate generation were assessed to evaluate the changes in glucose metabolism in human glioma U251 cells with small interfering RNA (siRNA)-mediated ENO1 knockdown. MTT assay and 5-ethynyl-2'-deoxyuridine (EdU) staining were used to examine the cell growth and cell cycle changes following siRNA transfection of the cells.<h4>Resul ...[more]