Ontology highlight
ABSTRACT:
SUBMITTER: Mano H
PROVIDER: S-EPMC6779754 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Mano Hiroaki H Asaoka Yoichi Y Asaoka Yoichi Y Kojima Daisuke D Fukada Yoshitaka Y
Communications biology 20191007
The pineal gland functioning as a photoreceptive organ in non-mammalian species is a serial homolog of the retina. Here we found that Brain-specific homeobox (Bsx) is a key regulator conferring individuality on the pineal gland between the two serially homologous photoreceptive organs in zebrafish. Bsx knock-down impaired the pineal development with reduced expression of <i>exorh</i>, the pineal-specific gene responsible for the photoreception, whereas it induced ectopic expression of <i>rho</i> ...[more]