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Hydrophilic Molecularly Imprinted Chitosan Based on Deep Eutectic Solvents for the Enrichment of Gallic Acid in Red Ginseng Tea.

ABSTRACT: Hydrophilic molecularly imprinted chitosan (HMICS) were synthesized based on hydrophilic deep eutectic solvents (DESs) and the DESs was used as both a template and functional monomer for the enrichment of gallic acid (GA) from red ginseng tea using a solid phase microextraction (SPME) method. Using the response surface methodology (RSM) strategy, the optimal extraction amount (8.57 mg·g-1) was found to be an extraction time of 30 min, a solid to liquid ratio of 20 mg·mL-1, and five adsorption/desorption cycles. Compared to traditional methods, the produced HMICS-SPME exhibited the advantages of simplicity of operation, higher recovery and selectivity, improved analytical characteristics and reduced sample and reagent consumption, and it is expected to promote the rapid development and wide applications of molecular imprinting.

SUBMITTER: Li G

PROVIDER: S-EPMC6780181 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Hydrophilic Molecularly Imprinted Chitosan Based on Deep Eutectic Solvents for the Enrichment of Gallic Acid in Red Ginseng Tea.

Li Guizhen G Row Kyung Ho KH

Polymers 20190901 9

Hydrophilic molecularly imprinted chitosan (HMICS) were synthesized based on hydrophilic deep eutectic solvents (DESs) and the DESs was used as both a template and functional monomer for the enrichment of gallic acid (GA) from red ginseng tea using a solid phase microextraction (SPME) method. Using the response surface methodology (RSM) strategy, the optimal extraction amount (8.57 mg·g<sup>-1</sup>) was found to be an extraction time of 30 min, a solid to liquid ratio of 20 mg·mL<sup>-1</sup>, ...[more]

PMID: 31480529

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