Ontology highlight
ABSTRACT:
SUBMITTER: Miklosz J
PROVIDER: S-EPMC6780366 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Miklosz Joanna J Kalaska Bartlomiej B Kaminski Kamil K Rusak Malgorzata M Szczubialka Krzysztof K Nowakowska Maria M Pawlak Dariusz D Mogielnicki Andrzej A
Marine drugs 20190917 9
Protamine sulfate (PS) is a polycationic protein drug obtained from the sperm of fish, and is used to reverse the anticoagulant effect of unfractionated heparin (UFH). However, the interactions between PS, UFH, and platelets are still not clear. We measured the platelet numbers and collagen-induced aggregation, P-selectin, platelet factor 4, β-thromboglobulin, prostacyclin metabolite, D-dimers, activated partial thromboplastin time, prothrombin time, anti-factor Xa, fibrinogen, thrombus weight a ...[more]