Ontology highlight
ABSTRACT:
SUBMITTER: Gaebler C
PROVIDER: S-EPMC6781006 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Gaebler Christian C Lorenzi Julio C C JCC Oliveira Thiago Y TY Nogueira Lilian L Ramos Victor V Lu Ching-Lan CL Pai Joy A JA Pai Joy A JA Mendoza Pilar P Jankovic Mila M Caskey Marina M Nussenzweig Michel C MC
The Journal of experimental medicine 20190726 10
HIV-1 infection requires lifelong therapy with antiretroviral drugs due to the existence of a latent reservoir of transcriptionally inactive integrated proviruses. The goal of HIV-1 cure research is to eliminate or functionally silence this reservoir. To this end, there are numerous ongoing studies to evaluate immunological approaches, including monoclonal antibody therapies. Evaluating the results of these studies requires sensitive and specific measures of the reservoir. Here, we describe a re ...[more]