Dataset Information

Extreme mito-nuclear discordance in a peninsular lizard: the role of drift, selection, and climate.

ABSTRACT: Nuclear and mitochondrial genomes coexist within cells but are subject to different tempos and modes of evolution. Evolutionary forces such as drift, mutation, selection, and migration are expected to play fundamental roles in the origin and maintenance of diverged populations; however, divergence may lag between genomes subject to different modes of inheritance and functional specialization. Herein, we explore whole mitochondrial genome data and thousands of nuclear single nucleotide polymorphisms to evidence extreme mito-nuclear discordance in the small black-tailed brush lizard, Urosaurus nigricaudus, of the Peninsula of Baja California, Mexico and southern California, USA, and discuss potential drivers. Results show three deeply divergent mitochondrial lineages dating back to the later Miocene (ca. 5.5?Ma) and Pliocene (ca. 2.8?Ma) that likely followed geographic isolation due to trans-peninsular seaways. This contrasts with very low levels of genetic differentiation in nuclear loci (FST?

SUBMITTER: Bernardo PH

PROVIDER: S-EPMC6781153 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Extreme mito-nuclear discordance in a peninsular lizard: the role of drift, selection, and climate.

Bernardo Pedro Henrique PH Sánchez-Ramírez Santiago S Sánchez-Pacheco Santiago J SJ Álvarez-Castañeda Sergio Ticul ST Aguilera-Miller Eduardo Felipe EF Mendez-de la Cruz Fausto Roberto FR Murphy Robert W RW

Heredity 20190304 3

Nuclear and mitochondrial genomes coexist within cells but are subject to different tempos and modes of evolution. Evolutionary forces such as drift, mutation, selection, and migration are expected to play fundamental roles in the origin and maintenance of diverged populations; however, divergence may lag between genomes subject to different modes of inheritance and functional specialization. Herein, we explore whole mitochondrial genome data and thousands of nuclear single nucleotide polymorphi ...[more]

PMID: 30833746

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Project description:As hybrid zones exhibit selective patterns of gene flow between otherwise distinct lineages, they can be especially valuable for informing processes of microevolution and speciation. The bumble bee, Bombus melanopygus, displays two distinct color forms generated by Müllerian mimicry: a northern "Rocky Mountain'' color form with ferruginous mid-abdominal segments (B. m. melanopygus) and a southern "Pacific'' form with black mid-abdominal segments (B. m. edwardsii). These morphs meet in a mimetic transition zone in northern California and southern Oregon that is more narrow and transitions further west than comimetic bumble bee species. To understand the historical formation of this mimicry zone, we assessed color distribution data for B. melanopygus from the last 100 years. We then examined gene flow among the color forms in the transition zone by comparing sequences from mitochondrial COI barcode sequences, color-controlling loci, and the rest of the nuclear genome. These data support two geographically distinct mitochondrial haplogroups aligned to the ancestrally ferruginous and black forms that meet within the color transition zone. This clustering is also supported by the nuclear genome, which, while showing strong admixture across individuals, distinguishes individuals most by their mitochondrial haplotype, followed by geography. These data suggest the two lineages most likely were historically isolated, acquired fixed color differences, and then came into secondary contact with ongoing gene flow. The transition zone, however, exhibits asymmetries: mitochondrial haplotypes transition further south than color pattern, and both transition over shorter distances in the south. This system thus demonstrates alternative patterns of gene flow that occur in contact zones, presenting another example of mito-nuclear discordance. Discordant gene flow is inferred to most likely be driven by a combination of mimetic selection, dominance effects, and assortative mating.

Dataset Information

Extreme mito-nuclear discordance in a peninsular lizard: the role of drift, selection, and climate.

Publications

Extreme mito-nuclear discordance in a peninsular lizard: the role of drift, selection, and climate.

Similar Datasets

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