Ontology highlight
ABSTRACT:
SUBMITTER: Yip SH
PROVIDER: S-EPMC6781572 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Yip Shun H SH Sham Pak Chung PC Wang Junwen J
Briefings in bioinformatics 20190701 4
Traditional RNA sequencing (RNA-seq) allows the detection of gene expression variations between two or more cell populations through differentially expressed gene (DEG) analysis. However, genes that contribute to cell-to-cell differences are not discoverable with RNA-seq because RNA-seq samples are obtained from a mixture of cells. Single-cell RNA-seq (scRNA-seq) allows the detection of gene expression in each cell. With scRNA-seq, highly variable gene (HVG) discovery allows the detection of gen ...[more]