Ontology highlight
ABSTRACT:
SUBMITTER: Brown WL
PROVIDER: S-EPMC6783943 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Brown William L WL Law Emily K EK Argyris Prokopios P PP Carpenter Michael A MA Levin-Klein Rena R Ranum Alison N AN Molan Amy M AM Forster Colleen L CL Anderson Brett D BD Lackey Lela L Harris Reuben S RS
Antibodies (Basel, Switzerland) 20190910 3
The DNA cytosine deaminase APOBEC3B (A3B) is normally an antiviral factor in the innate immune response. However, A3B has been implicated in cancer mutagenesis, particularly in solid tumors of the bladder, breast, cervix, head/neck, and lung. Here, we report data on the generation and characterization of a rabbit monoclonal antibody (mAb) for human A3B. One mAb, 5210-87-13, demonstrates utility in multiple applications, including ELISA, immunoblot, immunofluorescence microscopy, and immunohistoc ...[more]