Ontology highlight
ABSTRACT:
SUBMITTER: Omersa N
PROVIDER: S-EPMC6784129 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Omersa Neža N Podobnik Marjetka M Anderluh Gregor G
Toxins 20190919 9
Perforation of cellular membranes by pore-forming proteins can affect cell physiology, tissue integrity, or immune response. Since many pore-forming proteins are toxins or highly potent virulence factors, they represent an attractive target for the development of molecules that neutralize their actions with high efficacy. There has been an assortment of inhibitors developed to specifically obstruct the activity of pore-forming proteins, in addition to vaccination and antibiotics that serve as a ...[more]