Ontology highlight
ABSTRACT:
SUBMITTER: Lazarevic I
PROVIDER: S-EPMC6784188 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Lazarevic Ivana I Banko Ana A Miljanovic Danijela D Cupic Maja M
Viruses 20190824 9
Hepatitis B virus (HBV) reactivation occurs as a major complication of immunosuppressive therapy among persons who have recovered from acute hepatitis and those who have controlled chronic infection. Recent literature data emphasize the presence of a high degree of <i>S</i> gene variability in HBV isolates from patients who developed reactivation. In reactivated HBV, the most frequently detected mutations belong to the second loop of "<i>a</i>" determinant in HBsAg. These mutations were identifi ...[more]