Ontology highlight
ABSTRACT:
SUBMITTER: Tan S
PROVIDER: S-EPMC6784204 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Antibiotics (Basel, Switzerland) 20190811 3
Ribosomally-synthesized and post-translationally modified peptides (RiPPs) are a large class of natural products produced across all domains of life. The lasso peptides, a subclass of RiPPs with a lasso-like structure, are structurally and functionally unique compared to other known peptide antibiotics in that the linear peptide is literally "tied in a knot" during its post-translational maturation. This underexplored class of peptides brings chemical diversity and unique modes of action to the ...[more]