Ontology highlight
ABSTRACT:
SUBMITTER: Herrera-Ubeda C
PROVIDER: S-EPMC6784235 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Biology 20190824 3
Homologous long non-coding RNAs (lncRNAs) are elusive to identify by sequence similarity due to their fast-evolutionary rate. Here we develop LincOFinder, a pipeline that finds conserved intergenic lncRNAs (lincRNAs) between distant related species by means of microsynteny analyses. Using this tool, we have identified 16 bona fide homologous lincRNAs between the amphioxus and human genomes. We characterized and compared in amphioxus and <i>Xenopus</i> the expression domain of one of them, <i>Hot ...[more]