Ontology highlight
ABSTRACT:
SUBMITTER: Esseili MA
PROVIDER: S-EPMC6784273 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Esseili Malak A MA Gao Xiang X Boley Patricia P Hou Yixuan Y Saif Linda J LJ Brewer-Jensen Paul P Lindesmith Lisa C LC Baric Ralph S RS Atmar Robert L RL Wang Qiuhong Q
Viruses 20190908 9
Lettuce is often implicated in human norovirus (HuNoV) foodborne outbreaks. We identified H-like histo-blood group antigens (HBGAs) on lettuce leaves as specific binding moieties for virus-like particles (VLPs) of HuNoV GII.4/HS194/2009 strain. The objective of this study was to determine whether HuNoV-lettuce binding is mediated through the virus HBGA binding sites (HBS). Toward this objective, VLPs of historical HuNoV GII.4 strains (1987, 1997, 2002, 2004 and 2006) with known natural mutations ...[more]