Taste bud formation depends on taste nerves.
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ABSTRACT:
SUBMITTER: Fan D
PROVIDER: S-EPMC6785267 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Publications
Taste bud formation depends on taste nerves.
Fan Di D Chettouh Zoubida Z Consalez G Giacomo GG Brunet Jean-François JF
eLife 20191001
It has been known for more than a century that, in adult vertebrates, the maintenance of taste buds depends on their afferent nerves. However, the initial formation of taste buds is proposed to be nerve-independent in amphibians, and evidence to the contrary in mammals has been endlessly debated, mostly due to indirect and incomplete means to impede innervation during the protracted perinatal period of taste bud differentiation. Here, by genetically ablating, in mice, all somatic (i.e. touch) or ...[more]
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