Ontology highlight
ABSTRACT:
SUBMITTER: Liu D
PROVIDER: S-EPMC6785639 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Liu Dongjing D Wang Mengying M Yuan Yuan Y Schwender Holger H Wang Hong H Wang Ping P Zhou Zhibo Z Li Jing J Wu Tao T Zhu Hongping H Beaty Terri H TH
Molecular genetics & genomic medicine 20190816 10
<h4>Background</h4>Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common birth defect with complex etiology. One strategy for studying the genetic risk factors of NSCL/P is to consider gene-gene interaction (G × G) among gene pathways having a role in craniofacial development. The present study aimed to investigate the G × G among cell adhesion gene pathway.<h4>Methods</h4>We carried out an interaction analysis of eight genes involved in cell adherens junctions among 806 NSCL/ ...[more]