Ontology highlight
ABSTRACT:
SUBMITTER: Carissimo G
PROVIDER: S-EPMC6787436 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Carissimo Guillaume G Chan Yi-Hao YH Utt Age A Chua Tze-Kwang TK Bakar Farhana Abu FA Merits Andres A Ng Lisa F P LFP
Frontiers in microbiology 20190924
The evolutionarily conserved AAA+ ATPase valosin-containing protein (VCP) was previously shown to be a proviral host factor for several viruses from different viral families such as <i>Flaviviridae, Picornaviridae</i>, and <i>Herpesviridae</i>. VCP was shown to affect trafficking of Sindbis virus receptor and functions as a component of Semliki Forest virus (SFV) replicase compartment. However, the role of this cellular protein was not evaluated during replication of alphaviruses including chiku ...[more]