Ontology highlight
ABSTRACT:
SUBMITTER: Song S
PROVIDER: S-EPMC6787446 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Song Shangqing S Long Manmei M Yu Guopeng G Cheng Yajun Y Yang Qing Q Liu Jiayi J Wang Yiwei Y Sheng Jiayan J Wang Linhui L Wang Zhong Z Xu Bin B
Journal of cellular and molecular medicine 20190724 10
Exosome-derived miRNAs are regarded as biomarkers for the diagnosis and prognosis of many human cancers. However, its function in clear cell renal cell carcinoma (ccRCC) remains unclear. In this study, differentially expressed miRNAs from urinal exosomes were identified using next-generation sequencing (NGS) and verified using urine samples of ccRCC patients and healthy donors. Then, the exosomes were analysed in early-stage ccRCC patients, healthy individuals and patients suffering from other u ...[more]