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Bacterial microcompartments: catalysis-enhancing metabolic modules for next generation metabolic and biomedical engineering.

ABSTRACT: Bacterial cells have long been thought to be simple cells with little spatial organization, but recent research has shown that they exhibit a remarkable degree of subcellular differentiation. Indeed, bacteria even have organelles such as magnetosomes for sensing magnetic fields or gas vesicles controlling cell buoyancy. A functionally diverse group of bacterial organelles are the bacterial microcompartments (BMCs) that fulfill specialized metabolic needs. Modification and reengineering of these BMCs enable innovative approaches for metabolic engineering and nanomedicine.

SUBMITTER: Kirst H

PROVIDER: S-EPMC6787980 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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Bacterial microcompartments: catalysis-enhancing metabolic modules for next generation metabolic and biomedical engineering.

Kirst Henning H Kerfeld Cheryl A CA

BMC biology 20191010 1

Bacterial cells have long been thought to be simple cells with little spatial organization, but recent research has shown that they exhibit a remarkable degree of subcellular differentiation. Indeed, bacteria even have organelles such as magnetosomes for sensing magnetic fields or gas vesicles controlling cell buoyancy. A functionally diverse group of bacterial organelles are the bacterial microcompartments (BMCs) that fulfill specialized metabolic needs. Modification and reengineering of these ...[more]

PMID: 31601225

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