Ontology highlight
ABSTRACT:
SUBMITTER: Ding Y
PROVIDER: S-EPMC6788385 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Ding Yongfeng Y Zhong Tingting T Wang Min M Xiang Xueping X Ren Guoping G Jia Zhongjuan Z Lin Qinghui Q Liu Qian Q Dong Jingwen J Li Linrong L Li Xiawei X Jiang Haiping H Zhu Lijun L Li Haoran H Shen Dejun D Teng Lisong L Li Chen C Shao Jimin J
Frontiers in oncology 20191004
Mining cancer-omics databases deepens our understanding of cancer biology and can lead to potential breakthroughs in cancer treatment. Here, we propose an integrative analytical approach to reveal across-cancer expression patterns and identify potential clinical impacts for genes of interest from five representative public databases. Using ribonucleotide reductase (RR), a key enzyme in DNA synthesis and cancer-therapeutic targeting, as an example, we characterized the mRNA expression profiles an ...[more]