Ontology highlight
ABSTRACT:
SUBMITTER: Ke M
PROVIDER: S-EPMC6789186 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Ke Minjing M Chong Cheong-Meng CM Su Huanxing H
World journal of stem cells 20190901 9
Parkinson's disease (PD) is an age-related neurodegenerative disease caused by the progressive loss of dopaminergic (DA) neurons in the substantia nigra. As DA neurons degenerate, PD patients gradually lose their ability of movement. To date no effective therapies are available for the treatment of PD and its pathogenesis remains unknown. Experimental models that appropriately mimic the development of PD are certainly needed for gaining mechanistic insights into PD pathogenesis and identifying n ...[more]