Ontology highlight
ABSTRACT:
SUBMITTER: Goto T
PROVIDER: S-EPMC6789649 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Vaccines 20190826 3
Radiotherapy is generally considered to be a local treatment, but there have been reports of rare cases demonstrating abscopal effects in which antitumor effects have been observed in cancer lesions other than the irradiated site. This result is more likely to occur when immune checkpoint inhibitors are used in addition to radiotherapy. Certain radiation-induced chemokines and cytokines have immune-enhancing effects. Immune checkpoint inhibitors may strengthen these effects by stimulating antige ...[more]