Ontology highlight
ABSTRACT:
SUBMITTER: Bidokhti MRM
PROVIDER: S-EPMC6789684 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Bidokhti Mehdi R M MRM Ullman Karin K Hammer Anne Sofie AS Jensen Trine Hammer TH Chriél Mariann M Byrareddy Siddappa N SN Baule Claudia C
Vaccines 20190802 3
A full understanding of the immune response to astrovirus (AstV) infection is required to treat and control AstV-induced gastroenteritis. Relative contributions of each arm of the immune system in restricting AstV infection remain unknown. In this study, two novel subunit AstV vaccines derived from capsid protein (CP) of mink AstV (MAstV) such as CPΔN (spanning amino acids 161-775) and CPΔC (spanning amino acids 1-621) were evaluated. Their immunogenicity and cytokine production in mice, as well ...[more]