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Attitudes of Members of Genetics Professional Societies Toward Human Gene Editing.


ABSTRACT: Gene-editing technologies have improved in ease, efficiency, and precision. Although discussions are occurring around acceptable uses of human gene editing, limited data exist on the views of genetics-trained individuals. In 2017, we distributed an anonymous online survey to assess the attitudes of members of genetics professional societies toward gene editing (N?=?500). Virtually all respondents were supportive of somatic editing in basic-science (99.2%) and clinical (87.4%) research on nonreproductive human cells. Only 57.2% were supportive of germline-editing basic-science research; 31.9% supported the transfer of viable embryos to humans for clinical research. While most favored future therapeutic uses of somatic (96.6%) and germline (77.8%) editing, there was little support for enhancement in somatic (13.0%) or germline (8.6%) cells. This study describes attitudes toward gene editing from genetics professionals worldwide and contributes to ongoing discourse and policy guidance in this domain.

SUBMITTER: Armsby AJ 

PROVIDER: S-EPMC6791481 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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Attitudes of Members of Genetics Professional Societies Toward Human Gene Editing.

Armsby Alyssa J AJ   Bombard Yvonne Y   Garrison Nanibaa' A NA   Halpern-Felsher Bonnie L BL   Ormond Kelly E KE  

The CRISPR journal 20191001 5


Gene-editing technologies have improved in ease, efficiency, and precision. Although discussions are occurring around acceptable uses of human gene editing, limited data exist on the views of genetics-trained individuals. In 2017, we distributed an anonymous online survey to assess the attitudes of members of genetics professional societies toward gene editing (<i>N</i> = 500). Virtually all respondents were supportive of somatic editing in basic-science (99.2%) and clinical (87.4%) research on  ...[more]

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