Ontology highlight
ABSTRACT:
SUBMITTER: Mair A
PROVIDER: S-EPMC6791687 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Mair Andrea A Xu Shou-Ling SL Branon Tess C TC Ting Alice Y AY Bergmann Dominique C DC
eLife 20190919
Defining specific protein interactions and spatially or temporally restricted local proteomes improves our understanding of all cellular processes, but obtaining such data is challenging, especially for rare proteins, cell types, or events. Proximity labeling enables discovery of protein neighborhoods defining functional complexes and/or organellar protein compositions. Recent technological improvements, namely two highly active biotin ligase variants (TurboID and miniTurbo), allowed us to addre ...[more]