Ontology highlight
ABSTRACT:
SUBMITTER: Plotnikova O
PROVIDER: S-EPMC6792129 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Plotnikova Olga O Baranova Ancha A Skoblov Mikhail M
Frontiers in genetics 20191008
MicroRNAs play a key role in the regulation of gene expression. A majority of microRNA-mRNA interactions remain unidentified. Despite extensive research, our ability to predict human microRNA-mRNA interactions using computational algorithms remains limited by a complexity of the models for non-canonical interactions, and an abundance of false-positive results. Here, we present the landscape of human microRNA-mRNA interactions derived from comprehensive analysis of HEK293 and Huh7.5 datasets, alo ...[more]