Short- and medium-term follow-up of transcatheter closure of perimembranous ventricular septal defects.

ABSTRACT: BACKGROUND:Transcatheter closure of perimembranous ventricular septal defects is one of the greatest challenges in interventional cardiology. Short- and midium-term follow-up data for large samples are limited. This report presents our experience with transcatheter closure of perimembranous ventricular septal defects using an occluder. METHODS:Two hundred fifty-three patients included in the database of the Second Affiliated Hospital and Yuying Children's Hospital from January 2011- December 2015 with transcatheter closure of perimembranous ventricular septal defects and discharged from follow-up. All patients were invited for clinical and transthoracic echocardiography, electrocardiogram, and thoracic radiography check-up. RESULTS:Device implantation was successful in 252 of 253 patients (99.6%). The median age was 42?months (range 27-216?months). The median follow-up duration was 36?months (range 6-60?months). The mean defect diameter was 3.5?±?1.4?mm and the mean size of the ventricular septal defect rim below the aortic valve was 3.7?±?1.8?mm. The mean diameter of the devices used was 4?mm. Thirty-seven patients developed arrhythmia after the procedure and recovered within 24?months; four patients had hemolysis and four had moderate tricuspid valve regurgitation. No other serious adverse event occurred during the follow-up period. CONCLUSION:Transcatheter closure of perimembranous ventricular septal defects using an occluder is safe and effective in most patients.

SUBMITTER: Li H 

PROVIDER: S-EPMC6794751 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature