Fetal exposure to the maternal microbiota in humans and mice.
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ABSTRACT:
SUBMITTER: Younge N
PROVIDER: S-EPMC6795398 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Publications
Fetal exposure to the maternal microbiota in humans and mice.
Younge Noelle N McCann Jessica R JR Ballard Julie J Plunkett Catherine C Akhtar Suhail S Araújo-Pérez Félix F Murtha Amy A Brandon Debra D Seed Patrick C PC Seed Patrick C PC
JCI insight 20191003 19
Previous studies have demonstrated the presence of microbial DNA in the fetal environment. However, it remains unclear whether this DNA represents viable bacteria and how it relates to the maternal microbiota across body sites. We studied the microbiota of human and mouse dyads to understand these relationships, localize bacteria in the fetus, and demonstrate bacterial viability. In human preterm and full-term mother-infant dyads at the time of cesarean delivery, the oral cavity and meconium of ...[more]
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