Ontology highlight
ABSTRACT:
SUBMITTER: Tarashansky AJ
PROVIDER: S-EPMC6795480 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
eLife 20190916
Single-cell RNA sequencing has spurred the development of computational methods that enable researchers to classify cell types, delineate developmental trajectories, and measure molecular responses to external perturbations. Many of these technologies rely on their ability to detect genes whose cell-to-cell variations arise from the biological processes of interest rather than transcriptional or technical noise. However, for datasets in which the biologically relevant differences between cells a ...[more]