Recent developments in limited stage small cell lung cancer.
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ABSTRACT:
SUBMITTER: Higgins KA
PROVIDER: S-EPMC6795581 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Recent developments in limited stage small cell lung cancer.
Higgins Kristin A KA Gorgens Sophia S Sudmeier Lisa J LJ Faivre-Finn Corinne C
Translational lung cancer research 20190901 Suppl 2
Limited stage small cell lung cancer (LS-SCLC) remains a challenging disease, with 5-year overall survival ranging from 30-35% with current standard of care treatment consisting of thoracic radiation to 45 Gy in 30 fractions delivered twice daily, with concurrent platinum/etoposide chemotherapy, followed by prophylactic cranial irradiation (PCI). The randomized, phase III CONVERT study confirmed 45 Gy delivered twice daily to be the optimal radiation fractionation regimen, without significantly ...[more]
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