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Auditory Deficits in Audiovisual Speech Perception in Adult Asperger's Syndrome: fMRI Study.


ABSTRACT: Audiovisual (AV) integration deficits have been proposed to underlie difficulties in speech perception in Asperger's syndrome (AS). It is not known, if the AV deficits are related to alterations in sensory processing at the level of unisensory processing or at levels of conjoint multisensory processing. Functional Magnetic-resonance images (MRI) was performed in 16 adult subjects with AS and 16 healthy controls (HC) matched for age, gender, and verbal IQ as they were exposed to disyllabic AV congruent and AV incongruent nouns. A simple semantic categorization task was used to ensure subjects' attention to the stimuli. The left auditory cortex (BA41) showed stronger activation in HC than in subjects with AS with no interaction regarding AV congruency. This suggests that alterations in auditory processing in unimodal low-level areas underlie AV speech perception deficits in AS. Whether this is signaling a difficulty in the deployment of attention remains to be demonstrated.

SUBMITTER: Tietze FA 

PROVIDER: S-EPMC6795762 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Auditory Deficits in Audiovisual Speech Perception in Adult Asperger's Syndrome: fMRI Study.

Tietze Fabian-Alexander FA   Hundertmark Laura L   Roy Mandy M   Zerr Michael M   Sinke Christopher C   Wiswede Daniel D   Walter Martin M   Münte Thomas F TF   Szycik Gregor R GR  

Frontiers in psychology 20191010


Audiovisual (AV) integration deficits have been proposed to underlie difficulties in speech perception in Asperger's syndrome (AS). It is not known, if the AV deficits are related to alterations in sensory processing at the level of unisensory processing or at levels of conjoint multisensory processing. Functional Magnetic-resonance images (MRI) was performed in 16 adult subjects with AS and 16 healthy controls (HC) matched for age, gender, and verbal IQ as they were exposed to disyllabic AV con  ...[more]

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