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Association of Symptoms of Obstructive Lung Disease and All-Cause Mortality in Older Adult Smokers.


ABSTRACT: OBJECTIVES:This study aims to investigate the impact of respiratory symptoms in current and former smokers with and without obstructive lung disease (OLD) on all-cause mortality. DESIGN:Secondary analysis in a prospective cohort (the Health, Aging and Body Composition study). SETTING:Memphis, Tennessee, and Pittsburgh, Pennsylvania. PARTICIPANTS:Black and white men and women with a history of current and former smoking (N?=?596; 63% male and 37% female) aged 70-79 years followed for 13 years. Participants were categorized into 4 mutually exclusive groups based on symptom profile and forced expiratory volume in the 1st second to forced vital capacity ratio. The groups were Less Dyspnea-No OLD (N?=?196), More Dyspnea-No OLD (N?=?104), Less Dyspnea-With OLD (N?=?162), and More Dyspnea-With OLD (N?=?134). MEASUREMENTS:All-cause mortality. RESULTS:Overall, 53% in Less Dyspnea-No OLD, 63% in More Dyspnea-No OLD, 67% in Less Dyspnea-With OLD, and 84% in More Dyspnea-With OLD died within the 13- year follow up period (log-rank ?2 ?=?44.4, P?

SUBMITTER: Opina MTD 

PROVIDER: S-EPMC6800777 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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Association of Symptoms of Obstructive Lung Disease and All-Cause Mortality in Older Adult Smokers.

Opina Maria Theresa D MTD   Nicklas Barbara J BJ   Lovato James F JF   Files Daniel C DC   Kritchevsky Stephen B SB   Moore Wendy C WC  

Journal of the American Geriatrics Society 20190627 10


<h4>Objectives</h4>This study aims to investigate the impact of respiratory symptoms in current and former smokers with and without obstructive lung disease (OLD) on all-cause mortality.<h4>Design</h4>Secondary analysis in a prospective cohort (the Health, Aging and Body Composition study).<h4>Setting</h4>Memphis, Tennessee, and Pittsburgh, Pennsylvania.<h4>Participants</h4>Black and white men and women with a history of current and former smoking (N = 596; 63% male and 37% female) aged 70-79 ye  ...[more]

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