Socioeconomic status and DNA methylation from birth through mid-childhood: a prospective study in Project Viva.
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ABSTRACT:
SUBMITTER: Laubach ZM
PROVIDER: S-EPMC6802709 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Socioeconomic status and DNA methylation from birth through mid-childhood: a prospective study in Project Viva.
Laubach Zachary M ZM Perng Wei W Cardenas Andres A Rifas-Shiman Sheryl L SL Oken Emily E DeMeo Dawn D Litonjua Augusto A AA Duca Radu-Corneliu RC Godderis Lode L Baccarelli Andrea A Hivert Marie-France MF
Epigenomics 20190911 12
<b>Aim:</b> We investigated associations of prenatal socioeconomic status (SES) with DNA methylation at birth, and to explore persistence of associations into early (∼3 years) and mid-childhood (∼7 years) among 609 mother-child pairs in a Boston-area prebirth cohort. <b>Materials & methods:</b> First, we created a prenatal SES index comprising individual- and neighborhood-level metrics and examined associations of low (lowest 10%) versus high (upper 90%) SES with genome-wide DNA methylation in c ...[more]
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