Ontology highlight
ABSTRACT:
SUBMITTER: Hara S
PROVIDER: S-EPMC6803481 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Hara Satoko S Sasaki Takaharu T Satoh-Takayama Naoko N Kanaya Takashi T Kato Tamotsu T Takikawa Yui Y Takahashi Masumi M Tachibana Naoko N Kim Kwang Soon KS Surh Charles D CD Ohno Hiroshi H
Frontiers in immunology 20191015
The primary induction sites for intestinal IgA are the gut-associated lymphoid tissues (GALT), such as Peyer's patches (PPs) and isolated lymphoid follicles (ILFs). The commensal microbiota is known to contribute to IgA production in the gut; however, the role of dietary antigens in IgA production is poorly understood. To understand the effect of dietary antigens on IgA production, post-weaning mice were maintained on an elemental diet without any large immunogenic molecules. We found that dieta ...[more]