Ontology highlight
ABSTRACT:
SUBMITTER: San Segundo-Acosta P
PROVIDER: S-EPMC6803672 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
San Segundo-Acosta Pablo P Oeo-Santos Carmen C Navas Ana A Jurado Aurora A Villalba Mayte M Barderas Rodrigo R
Scientific reports 20191021 1
Olive pollen is a major cause of immunoglobulin E (IgE)-mediated allergy in Mediterranean countries. It is expected to become a worldwide leading allergenic source because olive cultivation is increasing in many countries. Ole e 15 belongs to the cyclophilin pan-allergen family, which includes highly cross-reactive allergens from non-related plant, animal and mold species. Here, the amino acid differences between Ole e 15 and its weak cross-reactive human homolog PPIA were grafted onto Ole e 15 ...[more]